| Spacecraft | Crew | Launch Vehicle | Launch Date | Accident Date | Description |
|---|---|---|---|---|---|
| Apollo 1 | Grissom, Virgil Ivan (Gus) White, Edward Higgins II. Chaffee, Roger Bruce |
Saturn-1B | - | 27.01.1967 | Cabin fire killed crew during launch rehersal |
| Soyuz 1 | Komarov, Vladimir Mikhailovich | Soyuz | 23.04.1967 | 24.04.1967 | Pilot was killed when landing parachute failed to untangle. |
| X-15A #3-F65 | Adams, Michael James | X-15A | 15.11.1967 | 15.11.1967 | X-15 entered spin at Mach 5, after reaching peak altitude, lost control and disintegrated. |
| Soyuz 11 | Dobrovolsky, Georgi Timofeyevich Patsayev, Viktor Ivanovich Volkov, Vladislav Nikolayevich |
Soyuz | 06.06.1971 | 30.06.1971 | Crew was killed, when cabin pressure was lost prior reentry. |
| Challenger (STS-51L) | Scobee, Francis Richard Smith, Michael John McNair, Dr. Ronald Erwin Onizuka, Ellison Shoji (El) Resnik, Dr. Judith Arlene Jarvis, Gregory Bruce McAuliffe, Sharon Christa Corrigan |
Shuttle | 28.01.1986 | 28.01.1986 | A leak in the right SRB, caused by a failed O-ring, led to destruction of the ET and the spacecraft at T+73 sec. |
| Columbia (STS-107) | Husband, Rick Douglas McCool, William Cameron (Willie) Anderson, Michael Philip (Mike) Brown, Dr. David McDowell Clark, Dr. Laurel Blair Salton Chawla, Dr. Kalpana Ramon, Ilan |
Shuttle | 16.01.2003 | 01.02.2003 | Spacecraft disintegrated on reentry in 60 km height. Failure originated in the left wing, which was damaged by falling insulation foam from the ET. |
